The endocannabinoid system is a complex network of signaling molecules, enzymes, and receptors found throughout the body and brain, which regulate the homeostatic balance of many physiological systems. Responsible for maintaining balance and responding to changing environmental conditions, the endocannabinoid system helps ensure that the body is in a state of homeostatic equilibrium. By modulating the release of neurotransmitters and controlling transmission of pain and other signals, it plays a fundamental role in maintaining health, comfort and pleasure.

See also: brain stem, delta wave, nitric oxide, serotonin system